Metastatic cancer of unknown primary
Protocolul terapeutic pentru metastazele limfoganglionare laterocervicale de carcinom spinocelular cu punct de plecare neprecizat.
Source: Romanian Journal of Medical Practice. Identifi cation of subgroups with favorable prognosis is of decisive importance for the therapy of patients with CUP syndrome, including prolonged survival from directed treatment.
Facing such a scenario, the only solution is following a sequence of investigations and therapy steps towards a correct and complete diagnosis if possible. We review the current literature data and present a personal case. There are many controversies regarding the primitive metastatic neck lymph nodes related to the optimum management, balanced with benefit for the patient.
The patients with neck node metastases metastatic cancer of unknown metastatic cancer of unknown primary occult head and neck cancer have clinical features and prognosis similar to other head and neck malignancies.
Treatment of patients with metastatic squamous cell carcinoma involving cervical lymph nodes of an unknown primary origin should be similar to that of patients with locally advanced carcinoma of the head and neck.
Therapeutic approaches include surgery lymph node excision or neck dissectionwith or without postoperative radiotherapy, radiotherapy alone and radiotherapy followed by surgery. In early stages N1neck dissection and radiotherapy seem to have similar efficacy, whereas more advanced cases N2- N3 necessitate combined approaches.
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The extent of radiotherapy irradiation of bilateral neck and mucosa versus ipsilateral neck radiotherapy remains debatable. A potential benefit from extensive radiotherapy should be weighted against its acute and late morbidity and difficulties in metastatic cancer of unknown primary in the case of subsequent primary emergence.
Protocolul de diagnostic pentru metastazele limfoganglionare laterocervicale cu punct de plecare neprecizat. Source: Romanian Journal of Medical Practice. In patients with CUP, no established concept exists for the necessary diagnostic procedures.
The role of other methods, such as chemotherapy and hyperthermia, remains to be determined. English Copyright of Romanian Journal of Medical Practice is the property of Empire Publishing House and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission.
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Наблюдая за ними на обзорном экране, он, еще не открыв люк, мог с легкостью читать выражение их лиц. Преобладающей эмоцией было любопытство - для Диаспара вещь сама по себе новая.
К нему подмешивалось опасение, а кое-где безошибочно распознавался настоящий страх. Никто не выглядел обрадованным его возвращением, с легкой грустью подумал Элвин. Совет, тем не менее, приветствовал его вполне корректно - хотя и не только из чистого дружелюбия.
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Unknown Primary Cancer - What Is It? Symptoms. Treatment.
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