MALIGNANT TUMORS OF DIGESTIVE ORGANS AND LIVER METASTASES AT THE TIME OF DIAGNOSIS
Abstract: Despite the significant progress regarding molecular classifications for colon, pancreatic and gastric cancer, the therapeutic methods arterial, chimio and radioembolizationthe life expectancy of patients with existing liver metastases did not improve significantly. The aim gastric cancer liver metastases to analyze the interrelation between the vascularization, mast cells and the histological growth pattern of hepatic metastasis with digestive origins.
The distribution of the liver metastasis gastric cancer liver metastases pattern was as follows: colon all 3 typespancreatic replacementgastric pushing type. A significant correlation between mast cell density in the peritumoral area and vascular microdensity in the metastatic domain of all histological growth patterns was found.
Significant correlation between positive mast cells tryptase density and degree of differentiation for the desmoplastic type was noticed.
The mast cells may have a prognostic role in this growth pattern and the mast cell inhibitor therapy may be useful. Keywords: gastric cancer liver metastases cells, liver metastasis, histological growth pattern References: 1.
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Several aspects of the oncological and surgical management are still controversial and so gastric cancer represents a challenge for the surgeon. This book aims to delineate the state of the art in the surgical and gastric cancer liver metastases treatment of gastric cancer, describing the new TNM staging system, the extent of visceral resection and lymphadenectomy focusing on the different open and minimally invasive surgical techniques and discussing intraoperative chemohyperthermia and neoadjuvant and adjuvant treatment.
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