Department of Ophthalmology, Grigore T. E-mail: moc.
We report the detection of HPV 52 in a sample taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye. The method used for the detection of HPV was real time polymerase chain reaction.
PCMC is more frequently found in males and it usually appears between the ages of 50 and Mendoza and Hedwig made the first contemporary description of squamous papilloma meaning eyelid-located tumour. Taking into consideration the rarity of this tumour, a diagnosis of certitude is difficult to establish until further investigations are made, in order to eliminate the primary malignant tumour with visceral location with mucine production that can metastasize at cutaneous level, as for example that of breast, gastrointestinal tract, lung, kidney, ovary, pancreas, or prostate. The metastatic lesions that originate from the breast or colon are prone to mimic the cutaneous mucinous carcinoma 4.
The evolution was favorable after surgical removal of the tumor and the patient was explained that long-term follow-up is essential to avoid recurrence. Keywords: Conjunctiva, eye, human papillomavirus 52, real time polymerase chain reaction, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, vagina, anushead and neck squamous papilloma meaning oral cavity, esophagus, larynxand nonmelanoma skin cancers squamous and squamous papilloma meaning cell carcinoma.
The association between HPV infection and eye tumors is little explored territory. Di Girolamo brings forward a two-hit theory that explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure squamous papilloma meaning causes squamous papilloma meaning alteration and the second hit is mediated by HPV infection in the susceptible cells.
Case Report We present a unique squamous papilloma meaning of squamous cell carcinoma of the conjunctiva examined and treated in June The year-old patient presented at the Ophthalmology Department for mild stinging sensation and redness in the left eye for almost 1-year and a half.
He has been treated for the last 2 months squamous papilloma meaning dexamethasone eye drops for scleritis by another ophthalmologist.
The patient admits squamous papilloma meaning a heavy smoker for almost 30 years and that in his free time he practices agriculture without using sunglasses. All other ophthalmological findings were normal.
Conjunctival culture was performed before surgery, and no bacterial infection was found. The CT scan of the head and neck showed no signs of tumor invasion of the orbit or the lymph nodes.
The limbic lesion was squamous papilloma meaning surgically with 2 mm margin of normal tissue and diathermy of the adjacent sclera was done. At the end, the remaining temporal defect was restored using a supero-nasal conjunctiva graft fixed in position with interrupted and surjet Squamous papilloma meaning excised tumor was cut into 2 fragments: One for pathology preserved in formalin and one for HPV genotyping preserved in Cobas polymerase chain reaction PCR solution and refrigerated at 4°C until processing.
Histopathology exam showed a moderate differentiated keratinized squamous cell carcinoma of the conjunctiva without koilocytosis [Figs.