This study was performed to evaluate the clinical risk profile of patients with ovarian tumors who were surgically treated, measuring the survival rate at 5 years.
Acceptarea rapidă de către chirurgi a amputației rectosigmoid cancer staging abdomino-perineale și renunțarea la exciziile locale practicate până atunci au dus la îmbunătățirea consistentă a controlului local al bolii. Miles sugera ca principiul rezecției în bloc a tumorii și a ganglionilor limfatici aplicat la cancerul de sân să fie aplicat și la cancerul rectal printr-un abord combinat — abdominal și perineal 4. În Dukes propunea o stadializare a cancerului colo-rectal care îmbina trei criterii rectosigmoid cancer staging statusul local, diseminarea limfatică loco-regională și diseminarea la distanță. Importanța stadializării Dukes este evidentă dacă ținem seama de faptul că o formă îmbunătățită a ei modificarea Astler-Coller - 5 continuă să fie larg folosită de chirurgi - cu toate că stadializarea TNM suverană în toate celelalte cancere digestive! Atât Miles, cât și Dukes, propuneau implicit un concept: boala neoplazică a rectului are o evoluție stadială cuantificabilă, iar în stadiile curabile este o boală compartimentală 6.
Furthermore, the surgical treatment by TNM stages was achieved, measuring the survival rate after five years of follow-up. Most of the patients with malignant disease were multiparous Moreover, from menopausal patients, the higher prevalence was seen at the group between 45 and 55 years old, not rectosigmoid cancer staging dependent on the earlier appearance.
The highest oxiuros q hacer of rectosigmoid cancer staging pathology was seen in women with polycystic ovaries i. Regarding serum CA tumoral rectosigmoid cancer staging, higher values were noticed in the majority of patients The highest prevalence of surgical treatment in the first and second stages was represented by total hysterectomy with bilateral anexectomy, rectosigmoid cancer staging and peritoneal lavage, and for the third and fourth stages, total hysterectomy, bilateral anexectomy, omentectomy, peritonectomy and lymphadenectomy, with a better survival rate at five years seen rectosigmoid cancer staging patients under the age of 30 years old.
Thus, our study shows the need to create a screening for patients at risk for ovarian cancer which present higher age, multiparity, early menarche, polycystic ovaries association, and higher serum CA marker values.
The survival rate at five years of folow-up shows a rectosigmoid cancer staging incidence of survival in patients under 30 years old, probably due to the earlier stages detected.
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Keywords malignant tumors, ovarian cancer, surgical treatment, management Rezumat Context. Acest studiu a fost efectuat pentru a evalua caracteristicile profilului de risc clinic al pacientelor cu tumori ovariene care au fost tratate chirurgical, măsurând rata rectosigmoid cancer staging supravieţuire la cinci ani. Mai mult, a fost realizat tratamentul chirurgical prin etapele TNM, măsurând rata de supravieţuire după cinci ani de urmărire. Mai mult, din de paciente la menopauză, prevalenţa crescută a fost observată la grupul cuprins între 45 şi 55 de ani, fără a depinde de precocitatea apariţiei.
Prevalenţa rectosigmoid cancer staging a tratamentului chirurgical în stadiile I şi II a fost reprezentată de histerectomie totală cu anexectomie bilaterală, omentectomie şi lavaj peritoneal, iar pentru stadiile III şi IV, de histerectomie totală, anexectomie bilaterală, omentectomie, peritonectomie şi limfadenectomie, cu o rată mai mare de supravieţuire la cinci rectosigmoid cancer staging la pacientele cu vârsta sub 30 de ani. Riscul apariţiei tumorilor ovariene maligne este asociat rectosigmoid cancer staging mult cu vârsta, paritatea, menarha timpurie, asocierea ovarelor polichistice şi bazată pe stadializarea TNM.
Rata de supravieţuire la cinci ani ulterior arată o incidenţă mai mare a supravieţuirii rectosigmoid cancer staging pacientele cu vârsta sub 30 de ani, probabil datorită detecţiei în stadiile incipiente. Cuvinte cheie tumori maligne cancer ovarian tratament chirurgical management Introduction Being the leading cause of gynecological diseases, ovarian tumors are rectosigmoid cancer staging as the fifth cause of death among women 1. Many of the published studies chisturi de giardia rectosigmoid cancer staging center analyses which enrolled only a small number of patients and the majority of reports were not relating to general population 7,8.
Clinical risk profile associated with ovarian cancer
Although many studies have been published about ovarian tumors, only a few have analyzed the importance of the clinical factors implicated 9. And currently, only a limited number of studies regarding detailed surgical staging have been published, including the survival rate of younger women diagnosed with ovarian tumors Although for most of the early-detected cases the treatment consisted in total hysterectomy, rectosigmoid cancer staging omentectomy, peritoneal biopsy and lymph node extraction, maximal cytoreductive surgery remains the basic surgery treatment for advanced ovarian tumors Besides many other tumoral markers involved in diagnosis and prognosis of ovarian cancer, serum cancer antigen CA is generally used in the differentiation of other pelvic mases 16, This marker can be evaluated as a prognostic factor, before the initiation of any treatment However, the implication of serum CA levels in rectosigmoid cancer staging cancer prognostic is more controversial, considering other variabilies such as staging The present study was undertaken on ovarian cancer patients, in which we proposed to determine the risk associated rectosigmoid cancer staging age, parity, menarche and menopause precocity, gynecological pathologies, serum CA tumoral marker, tumor, lymph node and metastasis TNM staging, and rectosigmoid cancer staging treatment associated with improved five-year survival outcome.
Our rectosigmoid cancer staging group consisted in patients with malignant ovarian tumors who were selected from a total of ovarian tumors which presented at least one ovarian tumor formation with a 5-mm minimal diameter.
All patients underwent surgery as primary treatment.
Profilul de risc clinic asociat cancerului ovarian
The study was approved by our institution, and the informed consent from each patient was taken. The inclusion criteria rectosigmoid cancer staging as follows: age between 15 years old and more than 60 years old at the time of rectosigmoid cancer staging initial diagnosis, all stages of ovarian neoplasms, and receiving only surgical treatment.
Rectosigmoid cancer staging excluded women with a detoxifiere beneficii of tubal sterilization techniques, pelvic radiation therapy either pre- or postoperatively, including pregnant women. The characteristics were expressed in percentages. Descriptive statistics was used in order to correlate the data.
Results Distribution by age Regarding the age of the patients, most malignant ovarian tumors were encountered in the age group over 60 years old, follwed by year-old patients, with Table 1.
Distribution of cases with malignant ovarian tumors by age Parity of the patients Out of the studied women, Figure 1. Distribution of cases Rectosigmoid cancer staging of menarche Malignant tumors occurred in patients Figure 2.
Distribution of cases with ovarian tumors depending Menopause precocity Of the cases analyzed, patients were menopausal, with the remaining 76 being in a younger age group.
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Out rectosigmoid cancer staging these, 44 Figure 3. Distribution of cases with ovarian tumors depending Association of gynecological pathology Malignant ovarian tumors were associated more with polycystic ovaries, in 13 patients 5.
Table 2. Distribution of ovarian cancers studied according to associated gynecological pathology Figure 4.
Ovarian tumors, intraoperative aspects personal archive Figure 5. Intraoperative aspects in ovarian tumors personal archive Serum CA tumoral rectosigmoid cancer staging Only cases of malignant tumors were tested for serum CA tumor marker. Out of these, Figure 6. The distribution of CA marker in the ovarian neoplasm in the study group TNM staging In stage I, there were 38 malignant ovarian tumors Stage II represented In the third stage, In the fourth stage, there were 49 malignant ovarian tumors rectosigmoid cancer staging Table 3.
Distribution of ovarian cancer patients studied according to TNM staging Surgical treatment The therapeutic strategies have been chosen according to the TNM stage. For stage Ia, unilateral anexectomy was chosen only under certain conditions. Adjuvant chemotherapy was not necessary in all cases.
Second-look laparoscopy was practiced at six months per-pelviscopic and was addressed to patients who apparently responded fully to chemotherapy or just to surgical treatment. This allows an assessment of residual risk and consolidation treatment, directing subsequent attitudes.
Thus, the following intervention was generally performed for the first and second stages: total hysterectomy with bilateral rectosigmoid cancer staging and omentectomy.
Therefore, malignant ovarian tumors in the first and second stages of development have received the following oxiuros y ivermectina treatments according to the TNM rectosigmoid cancer staging unilateral anexectomy in 8.
Table 4. Distribution of surgical treatment in the first and second stages of malignant ovarian tumo For the third and fourth stages, radical interventions were performed: hysterectomy with bilateral anexectomy with omentectomy, to which the large locoregional and visceral extensions could be added.
Ovarian cancers in the third and fourth stages were subjected to the following surgical interventions according to the TNM stage: total hysterectomy with bilateral anexectomy, with omentectomy, with rectosigmoid cancer staging and lymphadenectomy in 86 cases Table 5.