Department of Ophthalmology, Grigore T. E-mail: moc.
Endoscopic Resection of Sinonasal Inverted Papilloma
We report the detection of HPV 52 in a pathophysiology of nasal papilloma taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye. The method used for the detection of HPV was real time polymerase chain reaction.
- Detoxifierea organismului toamna
- Maxilectomia maxilară medială pentru papilomul inversat
- Human papillomavirus 52 positive squamous cell carcinoma of the conjunctiva
- Papillomavirus on foot
- [Nasal sinus papillomas].
The evolution was favorable after surgical removal of the tumor and the pathophysiology of nasal papilloma was explained that long-term follow-up is essential to avoid recurrence. Keywords: Conjunctiva, eye, human papillomavirus 52, real time polymerase chain reaction, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, vagina, anushead and neck cancers oral cavity, esophagus, larynxand nonmelanoma skin cancers squamous and basal cell carcinoma.
The association between HPV infection and eye tumors is little explored territory. Di Girolamo brings forward a two-hit theory that explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the pathophysiology of nasal papilloma hit is mediated by HPV infection in the susceptible cells.
Case Report We present a pathophysiology of nasal papilloma case of squamous cell carcinoma of the conjunctiva examined and treated in June The year-old patient presented at the Ophthalmology Department for mild stinging sensation and redness in the left eye for almost 1-year and a half.
He has been treated for the last 2 months with dexamethasone eye drops for scleritis by another ophthalmologist. The patient admits being a heavy smoker for almost 30 years and that in his free time he practices agriculture without using sunglasses.
All other ophthalmological findings were normal. Conjunctival culture was performed before surgery, and no bacterial infection was found. The CT scan of the head and neck showed no signs of tumor invasion of the orbit or the lymph nodes.
The limbic lesion was removed surgically with 2 mm margin of normal tissue and diathermy of the adjacent sclera was done. At the end, the remaining temporal defect was restored using a supero-nasal conjunctiva graft fixed in position with interrupted and surjet The excised tumor was cut into 2 fragments: One for pathology preserved in formalin and one for HPV genotyping preserved in Cobas polymerase chain reaction PCR solution and refrigerated at 4°C until processing.
The procedure implies surgical excision of the lateral nasal wall and ethmoid sinus. This technique is aided by the usage of adequate instruments, such as 0° and 70° scopes and angulated surgical instruments, which allow the complete visualization and access to the maxillary sinus. The authors present, as an endoscopic surgical atlas, step by step, the surgical procedure for endoscopic approach of inverted papilloma, in order to reach a complete tumor removal without any leftovers. Keywords medial maxillectomy, inverted papilloma, endoscopic sinus surgery Rezumat Tehnica maxilectomiei mediale reprezintă standardul de aur în tratamentul chirurgical al papilomului inversat, deoarece oferă o expunere adecvată a peretelul nazal lateral şi a sinusului maxilar.
Histopathology exam showed a moderate differentiated keratinized squamous cell carcinoma of the conjunctiva without koilocytosis [Figs.