Renin is an enzyme that controls aldosterone production. Aldosterone is produced by the adrenal glands located at the top of each kidney, in their outer portion called the adrenal cortex. Renin is produced by the kidneys and controls the activation of the hormone angiotensin, which stimulates the adrenal glands to produce aldosterone.
Papilloma virus blood test and renin tests are used to evaluate whether the adrenal papilloma virus blood test are producing appropriate amounts of aldosterone and to distinguish between the potential causes of excess or deficiency.
Aldosterone may be measured in the blood or in a hour urine sample, which measures the amount of aldosterone removed in the urine in a day.
Renin is always measured in blood. These tests are most useful in testing for primary aldosteronism, also known as Conn syndrome, which causes high blood pressure.
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If the test is positive, aldosterone production may be further evaluated with stimulation and suppression testing. Both aldosterone and renin levels are highest in the morning and vary throughout the day. They are affected by the body's position, by stress, and by a variety of prescribed medications.