Nicolau Institute of Virology, Bucharest, Romania.
Introduction: In human cancer cells DNMTs are responsible for both de novo and maintenance methylation of tumor suppressor genes. Design: 49 patients aged 1082 years hospitalized for thyroidectomy were included between January and July The inclusion criterion was patients with thyroid nodules with indication for surgery and the exclusion criteria were: hyperthyroidism, medullary thyroid anemia xarelto, thyroid metastasis, other thyroid tumors, and anaplastic thyroid carcinoma.
Patients were divided into three groups.
Adăugați în lista de dorințe Instalați Traduceți descrierea în română folosind Google Traducere? Traduceți descrierea înapoi în engleză Statele Unite ale Americii Traduceți Thyroid cancer is cancer that develops from the tissues of the thyroid gland. It is a disease in which cells grow abnormally and have the potential to spread to other parts of the body. Symptoms can include papillary thyroid cancer young age or a lump in the neck.
Group 1: 26 subjects with papillary thyroid carcinoma. Group 2: 14 patients with follicular adenoma. Group 3: nine patients with multinodular goiter.
Group 1 was divided in: Group 1. Total RNA was isolated from tissues and reverse transcribed.
Он проводил дни и недели, бродя по безлюдным башням на краю города в надежде отыскать где-нибудь выход во внешний мир.
- DNMT1 expression in papillary thyroid carcinoma | ECE
Это была концепция, обычная для множества древних верований, и представляется странным, что идея, не имевшая под собой ни малейшего рационального основания, стала в конце концов одной из величайших целей В естественной Вселенной никто никогда не встречал интеллект, лишенный телесной оболочки,-- продолжал Коллитрэкс.
- PAPILLARY - Definiția și sinonimele papillary în dicționarul Engleză
Double normalization was performed related to gene expression levels found in peritumoral tissues. SPSS 18 program was used to perform statistical analyze. The comparison of cancer subtypes did not reveal significant differences for DNMT1. DNMT1 expression did not correlate with tumor stage, tumor multifocality, capsular, vascular or lymphatic invasion or with metastasis.
Conclusion: DNMT1 is not overexpressed in papillary thyroid carcinoma and does not correlate with tumor stage, tumor multifocality, capsular, vascular or lymphatic invasion or with metastasis.